ZHANG QI　  WANG Yuanyuan　  WANG Weiqi

(Department of Electronic Engineering, Fudan University  Shanghai 200433)

MA Jianying QIAN Juying GE Junbo

(Department of Cardiology, Zhongshan Hospital of Fudan University  Shanghai 200032)

Received May 4, 2008

Revised Jun. 10, 2008

Abstract A method in proposed to simulate intravascular ultrasound (IVUS) images of atherosclerotic plagues. To accomplish the simulation of static IVUS plaque images, the ringdown and guidewire artifacts are introduces into the polar image-formation model (PIFM), and the fibrous, lipid and calcific contents are synthesized in plague respectively. The simulation of sequential IVUS images can be achieved by utilizing characteristics of the pulsatile artery. The results on static images demonstrate that it outperforms the PIFM method by 56.9% in terms of the correlation coefficient (CC), and 24.3% in terms of the mutual information (MI). The results on sequential images demonstrate that it outperforms the PIFM method by 51.0% in terms of CC, and 10.3% in terms of MI.　

PACS numbers: 43.35, 43.60